Experimental association between diabetes and pregnancy: renal effects for mothers in the postpartum period and possible signaling pathways involved
نویسندگان
چکیده
Materials and methods There were 4 groups (G): G1 (non-pregnant controls rats), females that received intraperitoneal injection (ipi) of 0.9% saline (s), G2 (non-pregnant diabetic rats), females that received ipi of alloxan (100 mg/kg) diluted in 0.9% s, G3 (control mothers), mothers that received ipi of 0.9% s and G4 (diabetic mothers), mothers that received ipi of alloxan (100 mg/kg) diluted in 0.9% s. The females with blood glucose above 150 mg/dL were considered diabetic. About 50 days after delivery for G3 and G4 and corresponding time for G1 and G2, the rats were subjected to structural and functional renal studies.
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